Based on nine cases of mesotheliomas the sensitivity for long microvilli as a marker for mesothelioma is 889 and the specificity is 100. Tem ultrastructure of cultured mesothelioma cells showed microvilli of various lengths in different cell lines but overall the microvilli in cultured mesothelioma cells were shorter than those observed in histological samples of mesothelioma.
A fine needle aspiration biopsy of a pleural lesion resulted in a fragment of tissue composed of loosely aggregated tumor cells many of which have a considerable portion of the cell surface covered with microvilli m.
Mesothelioma microvilli. Mustaersataariuwaeduau mesothelial cells form a monolayer of specialised pavement like cells that line the bodys serous cavities and internal organs. 1department of surgery university of western australia royal perth hospital perth 6000 wa australia. Epithelial cells have microvilli microscopic protrusions of the cell and clear structures called organelles within each cell.
The luminal surface is covered with microvilli. Mesothelioma pleural mass effusion biopsy shows malignancy em shows long microvilli hx of asbestos exposure sob nonpleuritic chest pain hx of asbestos exposure. Long microvilli were observed in eight of nine cases of mesothelioma but not in 50 cases of mesothelial hyperplasia or 50 cases of nonmucinous pulmonary adenocarcinoma fig.
Hammar et al 21 reported four cases of mucicarmine positive mesothelioma in which tubular crystalloids were found to be associated with the microvilli in all four cases as well as in the. Mesothelioma histology involves the study of cancerous mesothelial cells. The mesothelium is composed of an extensive monolayer of specialized cells mesothelial cells that line the bodys serous cavities and internal organs.
Doctors use these histological classifications to confirm the diagnosis. The proteins and serosal fluid trapped by the microvilli provide a slippery surface for internal organs to slide past one another. Int j biochem cell biol.
Microvilli are characteristic of mesothelial cells.
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