Mesothelioma Genetic | Mesothelioma Cancer

Can genes cause mesothelioma. Researchers found mesothelioma cells become much more responsive to chemotherapy when bap1 levels are restored and calcium channels are fixed and stabilized.

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In recent years a gene called bap1 was discovered that is also known to cause malignant mesothelioma among other cancers.

Mesothelioma genetic. Using genetics to treat mesothelioma. Although rare compared to asbestos exposure a mutation in the bap1 gene could explain a diagnosis of mesothelioma and risk to other family members especially if there was no exposure to asbestos. The genetic components of malignant mesothelioma are not well understood.

Signs and symptoms of mesothelioma may. Asbestos is the only proven cause of mesothelioma but not everyone exposed to asbestos later develops this cancerin fact a large majority of exposed people arent affected by the disease. This fact is why researchers investigate whether mesothelioma is hereditary.

A study published in june 2017 in the journal nature details why a person with bap1 mutations becomes more resistant to chemotherapy a common problem with mesothelioma patients. In addition genetic testing can be used to distinguish mesothelioma. Cancer researchers can biopsy and test tumors for specific genetic patterns using these patterns to diagnose and stage mesotheliomathis information is stored in genomic libraries and as more patients contribute their dna samples to the databases their accuracy in diagnosing mesothelioma improves.

Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs known as the mesothelium. Asbestos is the most important risk factor and cause of this cancer but individual genetics likely also play a role. Less commonly the lining of the abdomen and rarely the sac surrounding the heart or the sac surrounding the testis may be affected.

The most common area affected is the lining of the lungs and chest wall. Although genes do not directly cause malignant mesothelioma genetic factors influence cancer development after carcinogen.

Mesothelioma Genetic Research Team Receives 2 6m Grant From Nih